SUN PHARMACEUTICALS
Voraze 200mg Injection
Voraze 200mg Injection
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Introduction to Voraze 200mg Injection
Voraze 200mg injection is an antifungal drug that contains an active ingredient called Voriconazole. It belongs to the medication class known as fungal ergosterol synthesis inhibitor. It is prescribed for severe, life-threatening fungal infections and as a preventive measure for high-risk individuals, including those who have undergone bone marrow transplantation. This medicine should not be given to children younger than 2 years of age.
Do not take this medicine if you are allergic to Voraze 200mg injection or other medical ingredients. Before taking Voriconazole, it is important to notify your doctor if you have had an allergic reaction to other azoles, suffer from or have a history of liver disease, or have cardiomyopathy, irregular heartbeat, slow heart rate, or an abnormality of the electrocardiogram (ECG) called 'long QTc syndrome'. Additionally, it is crucial to avoid sunlight and sun exposure during treatment, protecting the skin with clothing and high-SPF sunscreen. Children should also follow these precautions. Some common side effects include fever, rash, nausea, vomiting, diarrhea, headache, swelling of the extremities, stomach pain, and breathing difficulties.
While on this medicine, promptly inform your doctor if you experience a sunburn, severe skin rash or blisters, bone pain, signs of adrenal insufficiency (chronic fatigue, muscle weakness, appetite loss, weight loss, abdominal pain), or signs of Cushing's syndrome (weight gain, fatty hump, rounded face, darkened skin, thinning skin, easy bruising, high blood sugar, excessive hair growth, excessive sweating). Inform your doctor if you have a known intolerance to certain sugars before taking Voraze 200mg injection because this medicine contains lactose.
Uses of Voraze 200mg Injection
- Invasive Aspergillosis
- Candidemia in non-neutropenic patients
- Esophageal candidiasis
- Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani)
- Candida infections
- Fungal infections in high-risk bone marrow transplant patients
Therapeutic Effects of Voraze 200mg Injection
Voraze 200mg injection works by blocking the production of ergosterol, disrupting fungal cell membranes and leading to cell death, ultimately eliminating the infection.
Interaction of Voraze 200mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Voraze 200mg injection and can cause undesirable side effects.
More Information about Voraze 200mg Injection
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Medicine should be used immediately, but if necessary may be stored for up to 24hrs at 2°C - 8°C.
- Always check the expiry date before consuming it.
How to consume Voraze 200mg Injection
Voraze 200mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in muscle or vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advice for Voraze 200mg Injection
Breast Feeding
Limited information is available on using Voraze 200mg injection during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
Alcohol
It is unsafe to consume alcohol while taking Voraze 200mg injection.
Liver
Voraze 200mg injection should be used cautiously in liver patients. Before starting the treatment, notify your doctor about pre-existing liver conditions. Dose adjustment is needed in such conditions. Your doctor will check your liver to monitor its functions.
Lungs
It is unknown whether Voraze 200mg injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Voraze 200mg injection could alter the driving ability or operating machinery capacity by causing blurred vision or uncomfortable sensitivity to light.
Pregnancy
Avoid taking Voraze 200mg injection during pregnancy unless directed by your doctor. Use effective contraception and notify your doctor immediately if you become pregnant while taking medicine.
Side Effects of Voraze 200mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Rash
- Visual disturbances
- Liver problems
- Arrhythmias and QT prolongation
- Jaundice (Changes in blood tests of liver function)
- Pancreatitis (inflammation of the pancreas)
Common
- Fever, headache
- Nausea, vomiting, diarrhea
- Swelling of the extremities
- Itchiness and rashes
- Sinusitis
- Pain in the stomach, back
- Blood in urine
- Seizures
- Low BP
- Hair loss
- Low levels of glucose, sodium, potassium, WBC, platelet
- Neutrophil counts in the blood.
Word of Advice
Liver and heart patients should take Voraze 200mg injection cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose.
Unless your doctor advises, do not consume this medicine if you are pregnant or breastfeeding while taking Voraze 200mg injection. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
FAQs about Voraze 200mg Injection
Q1.
What is the Mechanism of Action of Voraze 200mg Injection
Voraze 200mg Injection belongs to the class of antifungal medications. It works by inhibiting the production of ergosterol, an essential component of the fungal cell membrane. This disruption weakens the membrane structure, causing the fungal cells to break down and die, which helps in clearing the infection and relieving symptoms.
Q2.
Can you take Voraze 200mg injection when pregnant?
Consult your medical professional regarding the use of Voraze 200mg injection during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q3.
What is the Onset of Action of Voraze 200mg Injection
The effectiveness of Voraze 200mg Injection usually begins within a few days of starting the treatment. However, the exact duration may vary depending on the severity of the fungal infection, the site of infection, and the individual’s response to the medication. It is important to complete the full course as prescribed by your doctor for optimal results.
Q4.
What should I do if I miss a dose of Voraze 200mg injection?
If you miss a injection dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose the Voraze 200mg injection.
Q5.
What are the side effects of Voraze 200mg injection?
Some common side effects of Voraze 200mg injection are nausea, vomiting, diarrhea, swelling of the extremities, itchiness and rashes, sinusitis, pain in the stomach and back, blood in urine, seizures, and hair loss.
Fact Box of Voraze 200mg Injection
| Molecule Name: Voriconazole | Therapeutic class: Antifungal drug |
| Pharmacological class: Fungal ergosterol synthesis inhibitor |
Indications: 1. Invasive Aspergillosis 2. Candidemia in non-neutropenic patients 3. Esophageal candidiasis 4. Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani) 5. Candida infections 6. Fungal infections in high-risk bone marrow transplant patients |
